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Aired live on Los Angeles’ KTLA 5 on December 10, 2022, MPTF’s first live telethon is hosted by Yvette Nicole Brown and Tom Bergeron, and produced by Phil Rosenthal and David Wild. Thank you to our presenting sponsors, City National Bank and UCLA Health. To donate now, visit

Featuring special appearances by Margueritte Aozasa, Jeff Bridges, Julia Butters, Bryan Cranston, J. Rickley Dumm, Kevin Feige, Jodie Foster & Harry Northup, Jason George, Phil Gittelman, Tony Goldwyn & Anna Musky-Goldwyn, Clark Gregg, Kathryn Hahn, Kate Hudson, Hugh Jackman, Rian Johnson, Elle and Keegan-Michael Key, Tony Ludwig, Monica Macer, Ben Mankiewicz, Tim Matheson, Marlee Matlin, Janelle Monae, Edward Norton, Billy Porter, Parker Posey, Billy Ray, Phil Rosenthal, Richard Roundtree, June Squibb, and Kay Weissman.

Special musical performances by David Foster & Katharine McPhee, Susanna Hoffs, Jonas Myrin, Annette O’Toole & Michael McKean, and Brad Paisley. Phone bank hosted by KTLA’s Sam Rubin featuring Spencer Garrett, Clark Gregg, Michael McKean, Rob Morrow, Jessica Rothe, Alexandra Smothers, Adrienne Summer Visnic, and IATSE’s Mike Miller and Alex Aguilar Jr. Note: contains some adult language. This presentation does not include the Johnny Mathis performance present in the live telecast; view it here: